NCT07533786

A Clinical Trial Evaluating the Efficacy and Safety of HSK55718 in Patients for Postoperative Pain Treatment in Abdominal Surgery

A Multicenter, Randomized, Double-Blind, Double-Dummy, Placebo- and Active-Controlled Phase II Clinical Study to Evaluate the Efficacy and Safety of HSK55718 Injection for Postoperative Pain Treatment in Abdominal Surgery

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Haisco Pharmaceutical Group Co., Ltd. · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a multi-center, randomized, double-blind, double-dummy, placebo/active-controlled study. 200 subjects undergoing abdominal surgery under general anesthesia are planned to be enrolled and randomized into the HSK55718 group, morphine group, and placebo group.

Conditions

• Pain After Surgery

Interventions

Type	Name	Description
DRUG	HSK55718 dose level 1	Patients administrated with HSK55718 at dose level 1
DRUG	HSK55718 dose level 2	Patients administrated with HSK55718 at dose level 2
DRUG	HSK55718 dose level 3	Patients administrated with HSK55718 at dose level 3
DRUG	placebo	Patients administrated with placebo
DRUG	morphine	Patients administrated with morphine

Timeline

• Start date: 2026-04-20
• Primary completion: 2027-04-20
• Completion: 2027-04-20
• First posted: 2026-04-16
• Last updated: 2026-04-16

Locations

2 sites across 1 country: China