NCT07532135

Safety of Mulberry Leaf Extract Capsule on Blood Glucose Control in Healthy Volunteer

• Status: Recruiting
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 48 (estimated)
• Sponsor: Chulalongkorn University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Volunteers were divided into 2 groups: mulberry leaf extract capsule (DNJ 12mg) group and placebo group. They took the sample 3 times/day for 8 weeks. Complete blood count, Blood urea nitrogen (BUN), Creatinine, Aspartate transaminase (AST), Alanine aminotransferase (ALT), Alkaline phosphatase (ALP), Fasting plasma glucose, HbA1c, and adverse effects were evaluated before and after 4 and 8 weeks.

Detailed description

Volunteers were divided into 2 groups: mulberry leaf extract capsule (DNJ 12mg) group and placebo group. They took the sample 3 times/day for 8 weeks. Complete blood count, Blood urea nitrogen (BUN), Creatinine, Aspartate transaminase (AST), Alanine aminotransferase (ALT), Alkaline phosphatase (ALP), Fasting plasma glucose, HbA1c, and adverse effects were evaluated before and after 4 and 8 weeks. Satisfaction was assessed after 8 weeks.

Conditions

• Healthy Volunteers
• Non Diabetic Hyperglycemia

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Mulberry Leaf Extract	They took the Mulberry leaf extract capsule (DNJ 12mg) 3 times/day for 8 weeks.
OTHER	Placebo	They took the sample 3 times/day for 8 weeks.

Timeline

• Start date: 2025-10-01
• Primary completion: 2026-09-01
• Completion: 2026-09-24
• First posted: 2026-04-15
• Last updated: 2026-04-15

Locations

1 site across 1 country: Thailand