NCT07531875

Probiotics as Adjunctive Therapy in the Management of Periodontitis

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: University of Malaya · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trials is to learn about the effect of taking Prodentis on a long term basis following periodontal therapy. The main question it aims to answer is 1\. what is the effect of long-term consumption of Prodentis on regulating periodontal health and systemic immune-response, when compare to only taking it for 3 months post RSD?

Detailed description

Following root surface debridement (RSD), subjects in the control group (group NP) will be instructed to take Prodentis® twice/day immediately for 3 months only then continue 3 monthly review until month 12th. For subjects in the test group (group OP), following RSD, they will be instructed to take Prodentis® twice/day immediately for 3 months then continue Prodentis® once a day until month 12th. They will be reviewed 3 monthly.

Conditions

• Periodontitis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Prodentis	Non-surgical periodontal therapy

Timeline

• Start date: 2025-11-10
• Primary completion: 2028-11-01
• Completion: 2028-12-01
• First posted: 2026-04-15
• Last updated: 2026-04-15

Locations

1 site across 1 country: Malaysia