Trials / Completed
CompletedNCT07531797
Effect of High Frequency Cerebellar Repetitive Transcranial Magnetic Stimulation on Functional Ambulation of Patients With Cerebral Small Vessel Disease
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- Ain Shams University · Academic / Other
- Sex
- All
- Age
- 30 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to evaluate the effect of repetitive transcranial magnetic stimulation (rTMS) applied over the cerebellum on gait performance and balance in patients with cerebral small vessel disease (CSVD). CSVD is associated with impaired mobility and increased risk of falls, which can significantly affect functional independence and quality of life. Participants will be randomly assigned to receive either active cerebellar rTMS or sham stimulation over a defined treatment period. Gait and balance will be assessed using objective clinical measures, including the Timed Up and Go test (TUG) and the 10-Meter Walk Test (10MWT), at baseline, after the intervention, and during follow-up. The study aims to determine whether active cerebellar rTMS leads to greater improvement in motor function and mobility compared to sham stimulation in patients with CSVD.
Conditions
- Cerebral Small Vessel Disease
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Balance
- Gait Disorders
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Repetitive Transcranial Magnetic Stimulation | Repetitive transcranial magnetic stimulation (rTMS) will be applied over the cerebellum using a magnetic coil (figure of eight coil)to deliver repetitive pulses at specified frequency (10 HZ) according to the study protocol. |
| DEVICE | Sham Repetitive Transcranial Magnetic Stimulation | Sham repetitive transcranial magnetic stimulation will be applied over the cerebellum using a sham or inactive stimulation technique that mimics the procedure, sound, and sensation of active rTMS without delivering effective magnetic stimulation. |
Timeline
- Start date
- 2023-05-01
- Primary completion
- 2024-08-30
- Completion
- 2025-12-30
- First posted
- 2026-04-15
- Last updated
- 2026-04-15
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT07531797. Inclusion in this directory is not an endorsement.