NCT07531407

The Effects of Dexamethasone and Ibuprofen on Postoperative Analgesia in Patients Undergoing Hand and Forearm Surgery With Axillary Brachial Plexus Block

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 79 (actual)
• Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study aims to comparatively examine the effects of preemptive IV dexamethasone and IV ibuprofen use on the duration of analgesia in ultrasound-guided ABPB (Axillary Brachial Plexus Block) applications for patients undergoing hand and forearm surgery. Furthermore, investigating the relationship between the study drugs and the incidence of PONV (Postoperative Nausea and Vomiting) and determining the time until the first use of rescue analgesic are also among the secondary objectives.

Conditions

• Axillary Block
• Dexamethasone
• Ibuprofen
• Hand Surgery
• Forearm Surgery
• Postoperative Analgesia

Interventions

Type	Name	Description
DRUG	IV Dexamethasone 8mg	Patients who are in group D had intravenouse 8 mg dexamethasone before axillary brachial plexus blockade.
DRUG	iv ibuprofen	Patients who are in group I had intravenouse 400 mg ibuprofen before axillary brachial plexus blockade.

Timeline

• Start date: 2025-05-01
• Primary completion: 2025-10-31
• Completion: 2025-10-31
• First posted: 2026-04-15
• Last updated: 2026-04-15

Locations

1 site across 1 country: Turkey (Türkiye)

Regulatory

• FDA-regulated drug study