NCT07530289

A Clinical Study of Ulonivirine (MK-8507) With Atorvastatin and Metformin in Healthy Adults (MK-8507-018)

A Phase 1, Open-Label, Two-Period Fixed Sequence Study to Evaluate the Effects of a Single Oral Dose of Ulonivirine (MK-8507) on the Single-Dose Pharmacokinetics of Atorvastatin and Metformin in Healthy Adult Participants

• Status: Not Yet Recruiting
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 12 (estimated)
• Sponsor: Merck Sharp & Dohme LLC · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

Researchers want to learn about ulonivirine when given with atorvastatin and metformin in healthy people. The goal of this study is to compare the amount of atorvastatin and metformin in a person's body over time when given with and without ulonivirine.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Atorvastatin	Oral tablet
DRUG	Metformin	Oral tablet
DRUG	Ulonivirine	Oral tablet

Timeline

• Start date: 2026-05-01
• Primary completion: 2026-06-03
• Completion: 2026-06-17
• First posted: 2026-04-15
• Last updated: 2026-04-15

Regulatory

• FDA-regulated drug study