NCT07530250

Assessing Two Coenzyme Q10 Products in Men and Women

A Randomized, Double-blind, Crossover Study to Assess the Relative Bioavailability of Two Coenzyme Q10 Products in Men and Women

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Midwest Center for Metabolic and Cardiovascular Research · Academic / Other
• Sex: All
• Age: 21 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to compare the relative bioavailability of coenzyme Q10 (CoQ10) from acute administrations of a CoQ10 product designed for enhanced absorption versus a standard CoQ10 product in healthy men and women. Participants will be asked to come to the clinical on five different occasions, including a screening visit (visit 1, -7 days), two test 1 visits (visits 2 and 3, days 0 and 1), and two test 2 visits (visits 4 and 5, days 7 and 8). During the start of each test visit (visits 2 and 4), the participant will consume each study product with water and a standardized breakfast meal. Then, blood samples will be collected over a 10-hour period, and a standardized lunch, dinner, and snacks will be provided. The participant will return to the clinic the next morning for a blood draw 24 hours after the study product ingestion from the previous day. The same procedures will be repeated 7 to 14 days later with the other study product.

Detailed description

The study products will include 100 mg CoQ10 product designed for high absorption (administered as two 50 mg capsules) and 100 mg standard CoQ10 product (administered as two 50 mg capsules).

Conditions

• CoQ10 Blood Levels

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	high absorption CoQ10 product	100 mg CoQ10 product designed for high absorption (administered as two 50 mg capsules)
DIETARY_SUPPLEMENT	standard CoQ10 product	100 mg standard CoQ10 product (administered as two 50 mg capsules)

Timeline

• Start date: 2026-04-01
• Primary completion: 2026-07-01
• Completion: 2026-07-01
• First posted: 2026-04-15
• Last updated: 2026-04-17

Locations

1 site across 1 country: United States