NCT07530003

HUMSCs Combined With Col I to Third-Degree Burn Wound

A Single-Center, Randomized, Double-Blind, Placebo-Controlled Exploratory Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Combined With Bovine Type I Collagen for Promoting Third-Degree Burn Wound Repair

• Status: Recruiting
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 108 (estimated)
• Sponsor: The First Affiliated Hospital of Xinxiang Medical College · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the safety and tolerability of human umbilical cord mesenchymal stem cells combined with bovine type I collagen in the treatment of third-degree burn wounds.

Conditions

• Burn Wounds
• Third-Degree Burn Wounds

Interventions

Type	Name	Description
COMBINATION_PRODUCT	HUMSCs combined with bovine type I collagen	To evaluate the safety and tolerability of human umbilical cord mesenchymal stem cells combined with bovine type I collagen in the treatment of third-degree burn wounds
BIOLOGICAL	bovine type I collagen	To evaluate the safety and tolerability of bovine type I collagen in the treatment of third-degree burn wounds
DEVICE	Sterile blank dressing / Vaseline gauze	To evaluate the safety and tolerability of sterile blank dressing / vaseline gauze in the treatment of third-degree burn wounds.

Timeline

• Start date: 2026-04-06
• Primary completion: 2027-12-31
• Completion: 2028-12-31
• First posted: 2026-04-14
• Last updated: 2026-04-14

Locations

1 site across 1 country: China