Trials / Not Yet Recruiting
Not Yet RecruitingNCT07528508
A Clinical Trial in Healthy Participants to Study the Effect of a Single Dose of MK-8527 on Levels of Methadone (MK-8527-020)
A Clinical Trial to Study the Effect of a Single Dose of MK-8527 on the Pharmacokinetics of Methadone
- Status
- Not Yet Recruiting
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 14 (estimated)
- Sponsor
- Merck Sharp & Dohme LLC · Industry
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
The goal of this study is to learn about the effect of a study medicine called MK-8527 when taken with methadone. The study will also measure what happens to the methadone in a healthy person's body over time after MK-8527 is taken.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | MK-8527 | Tablet for oral administration. |
| DRUG | Methadone | Formulated per local guidelines, administered orally. |
Timeline
- Start date
- 2026-05-18
- Primary completion
- 2026-08-10
- Completion
- 2026-08-10
- First posted
- 2026-04-14
- Last updated
- 2026-04-14
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT07528508. Inclusion in this directory is not an endorsement.