NCT07526467

Video-EEG Semiological Patterns in PNES

Distinct Semiological Clusters of Psychogenic Non-Epileptic Seizures Identified by Video-EEG Monitoring

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Tepecik Training and Research Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This retrospective observational study evaluates semiological and electroclinical characteristics of psychogenic nonepileptic seizures (PNES) in adult patients who underwent video-EEG monitoring. The study aims to identify distinct semiological patterns and classify PNES events based on observable ictal features recorded during video-EEG monitoring.

Detailed description

Psychogenic nonepileptic seizures (PNES) are paroxysmal events that resemble epileptic seizures but are not associated with ictal epileptiform activity on electroencephalography (EEG). Video-EEG monitoring is the gold standard for diagnosis. In this retrospective observational study, video-EEG recordings and clinical data of 52 adult patients diagnosed with PNES were reviewed. Semiological features observed during recorded events were systematically evaluated and coded as binary variables. Hierarchical cluster analysis (Ward's method with squared Euclidean distance) was used to identify semiological patterns. The aim was to define clinically meaningful clusters of PNES events and to describe their demographic and clinical correlates.

Conditions

• Pnes

Timeline

• Start date: 2025-09-01
• Primary completion: 2025-12-01
• Completion: 2026-04-01
• First posted: 2026-04-13
• Last updated: 2026-04-13

Locations

1 site across 1 country: Turkey (Türkiye)