NCT07524842

Clinical Performance of Three Different Restorative Materials

Clinical Performance of Three Different Restorative Materials-Nanohybrid, Bulk-fill, and Alkasite-based

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Hacettepe University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The clinical performance of a bioactive composite (alkasite-based), a nanohybrid resin composite and a bulk-fill resin composite in class II restorations will be evaluated and compared. After recruiting participants with at least 3 approximal caries lesions, all restorations will be placed by a single clinician. All caries lesions will be removed before restoring. Cavities will be divided into three groups: a bioactive composite \[Cention Forte Ivoclar Vivadent, Schaan, Liechtenstein\], a nanohybrid resin composite \[Tetric N-Ceram2 (Ivoclar Vivadent, Schaan, Liechtenstein)\] and a bulk-fill resin composite \[Tetric N-PowerFill2 (Ivoclar Vivadent, Schaan, Liechtenstein)\], All restorative procedures will be conducted according to manufacturers' instructions. Restorations will be scored using FDI criteria after a week (baseline) 6, 12, 24, 36 and 48 months. Descriptive statistics will be performed using chi-square tests.

Conditions

• Tooth Disease

Interventions

Type	Name	Description
DEVICE	bioactive composite	bioactive composite restoration
DEVICE	nanohybrid resin composite	nanohybrid resin composite restoration
DEVICE	bulk-fill resin composite	bulk-fill resin composite restoration

Timeline

• Start date: 2026-04-28
• Primary completion: 2026-06-28
• Completion: 2028-06-28
• First posted: 2026-04-13
• Last updated: 2026-04-13