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RecruitingNCT07522931

Morphometric Study of the Female Pelvic and Lower Abdominal Retroperitoneum in Cadavers

Systematic Anatomical Description of the Female Pelvic and Lower Abdominal Retroperitoneum: A Descriptive and Morphometric Cadaveric Study Oriented to Gynecologic Surgery

Status
Recruiting
Phase
Study type
Observational
Enrollment
20 (estimated)
Sponsor
Hospital Universitari de Bellvitge · Academic / Other
Sex
Female
Age
18 Years
Healthy volunteers
Accepted

Summary

This study aims to provide a systematic anatomical and morphometric description of the female pelvic and lower abdominal retroperitoneum using cadaveric dissection, with direct application to gynecologic surgery. Standardized dissections will be performed in adult female cadavers obtained from a body donation program. Key anatomical structures, including the ureter, iliac vessels, aorta, inferior vena cava, hypogastric plexuses, and lymphatic territories, will be identified and measured. Spatial relationships, distances, and anatomical variations will be recorded using direct measurements and standardized photographic documentation. The study will quantify anatomical variability and asymmetry between right and left hemipelves, focusing on ureteral, vascular, and neural structures. The results are expected to improve surgical planning, particularly in nerve-sparing techniques and pelvic and para-aortic lymphadenectomy, and to support the development of an applied anatomical atlas for educational and clinical use.

Detailed description

This is an observational, descriptive, and morphometric cadaveric study designed to analyze the anatomy of the female pelvic and lower abdominal retroperitoneum with direct application to gynecologic surgery. The study will be conducted in adult female cadavers obtained from an institutional body donation program. Approximately 20 cadavers are expected to be included, depending on availability. Each hemipelvis will be considered an independent unit of analysis for side-to-side comparison. Standardized anatomical dissections will be performed following a predefined protocol. The retroperitoneum will be systematically exposed to identify and analyze key structures, including the ureter, iliac vessels and their branches, abdominal aorta, inferior vena cava, hypogastric plexuses, pelvic splanchnic nerves, and lymphatic territories. Morphometric measurements will be obtained using millimetric instruments and predefined anatomical reference points to ensure reproducibility. Variables will include distances between anatomical structures, vessel diameters, nerve relationships, and spatial organization of pelvic surgical spaces. All measurements will be performed at least twice, and standardized photographic documentation will be obtained. Primary outcomes include quantitative morphometric parameters and spatial relationships between key anatomical structures, as well as the frequency of anatomical variations. Secondary outcomes include characterization of ureteral variants, iliac branching patterns, presence and morphology of corona mortis, organization of the pelvic autonomic nervous system, and assessment of right-left anatomical asymmetry. Statistical analysis will be descriptive, including measures of central tendency and dispersion for continuous variables, and frequency distributions for categorical variables. Comparative analyses between hemipelves will be performed using paired statistical tests. This study does not involve living human participants, clinical interventions, or identifiable personal data. All procedures will be conducted in accordance with institutional and ethical standards for the use of donated human bodies for research and education. The expected outcome is the development of a clinically oriented anatomical dataset and an illustrated anatomical atlas to support surgical training, improve understanding of pelvic anatomy, and optimize surgical approaches in gynecologic oncology.

Conditions

Interventions

TypeNameDescription
OTHERAnatomical DissectionStandardized anatomical dissection of the pelvic and lower abdominal retroperitoneum in cadaveric specimens, including systematic identification of anatomical structures, direct morphometric measurements, and standardized photographic documentation.

Timeline

Start date
2026-04-14
Primary completion
2026-09-28
Completion
2026-11-30
First posted
2026-04-13
Last updated
2026-04-17

Locations

2 sites across 1 country: Spain

Source: ClinicalTrials.gov record NCT07522931. Inclusion in this directory is not an endorsement.