NCT07522268

Laser Pulpotomy: a Modern-non Pharmacological Alternate to Ferric Sulphate Pulpotomy

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 84 (actual)
• Sponsor: Shaheed Zulfiqar Ali Bhutto Medical University · Academic / Other
• Sex: All
• Age: 4 Years – 8 Years
• Healthy volunteers: Accepted

Summary

Diode lasers could be a viable alternative to ferric sulphate in pulpotomy.

Detailed description

Ferric sulphate (FS) has recently replaced formocresol as it has comparable clinical and radiographic outcomes, and is more biocompatible, making it the current material of choice. 6,7 However, some histological studies report inflammatory response caused by FS in the remaining pulp, similar to FC, which may lead to internal resorption and eventually, premature tooth exfoliation. In contrast to ferric sulphate, diode lasers due to their better antimicrobial action, cell regenerative properties, localized/controlled, and quick mechanism of action, are now being considered as an effective method of pulpotomy in dentistry. Even with several studies that have been conducted on the efficacy and success of laser pulpotomy, there is still a need for additional data and evidence that would further advocate its use in pulpotomy. Furthermore, there hasn't been any such study conducted in this region, which also highlights the importance of this study.

Conditions

• Pulpotomy

Interventions

Type	Name	Description
PROCEDURE	Group B (Diode Laser)	Group B (Diode Laser)
COMBINATION_PRODUCT	(Ferric Sulphate)	After hemostasis was achieved a sterile cotton pellet soaked in 15.5% ferric sulphate solution (Quickstat-FS, USA) was placed over amputated root stumps for 15-20 seconds.

Timeline

• Start date: 2019-06-01
• Primary completion: 2021-01-01
• Completion: 2021-01-01
• First posted: 2026-04-13
• Last updated: 2026-04-14

Locations

1 site across 1 country: Pakistan