NCT07518758

Acute Effect of Polyphenols Supplementation on Endothelial Function and Exercise Related Markers, in Physically Active Healthy Volunteers.

Effets Aigus d'Une supplémentation en polyphénols (Vinitrox™) Contre Placebo Sur la Fonction endothéliale et la Performance Lors d'un Exercice à intensité modérée en Hypoxie Chez Des Volontaires Sains Physiquement Actifs.

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 38 (estimated)
• Sponsor: Nexira · Industry
• Sex: All
• Age: 35 Years – 55 Years
• Healthy volunteers: Accepted

Summary

To evaluate the effect of acute polyphenols supplementation on vasodilation and related markers along with exercise related markers (notably performance, respiratory exchanges, perceived exertion), before, during and after a hypoxic moderate-intensity exercise in healthy recreative volunteers.

Detailed description

Exercise session is an ergometer cycling workout performed under hypoxia condition equivalent to 3000 meters of altitude. Exercise session is composed of a warmup period followed by 20 minutes of cycling starting at 60% of individual maximal aerobic power.

Conditions

• Vasodilation
• Exercise
• Healthy Adults

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Oral administration	2 capsules the day before and 2 capsules 2 hours before the exercise session

Timeline

• Start date: 2025-09-01
• Primary completion: 2026-04-20
• Completion: 2026-04-27
• First posted: 2026-04-09
• Last updated: 2026-04-13

Locations

1 site across 1 country: France