NCT07518563

Neural Synchronization During Gesture Production and Comprehension in Individuals With Aphasia and Healthy Controls: A Study Using EEG Hyperscanning

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 7 (actual)
• Sponsor: IRCCS San Camillo, Venezia, Italy · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This study explores the neural mechanisms of gesture comprehension and production in people with aphasia (PWA) and healthy controls, focusing on brain synchronization during gesture observation and reproduction. Using EEG hyperscanning, neural coupling between the encoder (PWA) and decoder (healthy participant) was analyzed during tasks involving social, affective, and informative gestures with both positive and negative emotional valence.

Detailed description

Gestures are essential in non-verbal communication, complementing speech by expressing emotions, intentions, and cognitive states. This study examines neural mechanisms of gesture comprehension and production in people with aphasia (PWA) and healthy controls, focusing on brain synchronization during gesture observation and reproduction. Using EEG hyperscanning, we analyzed neural coupling between the encoder (PWA) and decoder (healthy participant) during tasks involving social, affective, and informative gestures with both positive and negative emotional valence. Methods: Seven dyads of participants participated in this study. The research was approved by the Ethical Committee of the IRCCS San CamilloHospital

Conditions

• Aphasia
• Gestures

Interventions

Type	Name	Description
BEHAVIORAL	Person with Aphasia	EEG during gestures production

Timeline

• Start date: 2022-06-01
• Primary completion: 2023-08-01
• Completion: 2023-08-01
• First posted: 2026-04-08
• Last updated: 2026-04-08

Locations

1 site across 1 country: Italy