NCT07518238

Hernia Abd Wall Recons - BDE vs Exparel

Comparative Effectiveness of Bupivacaine-Dexamethasone-Epinephrine Versus Exparel in Postoperative Outcomes for Hernia Patients Undergoing Abdominal Wall Reconstruction

• Status: Enrolling By Invitation
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 128 (estimated)
• Sponsor: Baylor Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This trial compares how two different numbing medications help patients feel the least amount of pain while recovering from surgery.

Detailed description

This will be a prospective randomized controlled trial comparing the outcomes of hernia patients receiving BDE versus Exparel before abdominal wall reconstruction. The study will utilize the pain numeric rating scale (PNRS) validated questionnaire to assess pain levels. Patients will be asked to report their worst pain imaginable.

Conditions

• BDE for Hernia Patients
• Exparel for Hernia Patients

Interventions

Type	Name	Description
DRUG	BDE Injectable Drug	Bupivacaine, Dexamethasone, Epinephrine for hernia patients receiving abdominal wall reconstruction
DRUG	Exparel Injectable Drug	Exparel for hernia patients receiving abdominal wall reconstruction

Timeline

• Start date: 2026-01-13
• Primary completion: 2029-11-12
• Completion: 2029-11-12
• First posted: 2026-04-08
• Last updated: 2026-04-08

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study