NCT07514221

Project Yes+ for Young MSM Living With HIV in Vietnam

Adaptation of Project Yes+ to Improve Mental Health and Reduce HIV-related Stigma Among Adolescent and Young Men Who Have Sex With Men Living With HIV in Vietnam

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Hanoi Medical University · Academic / Other
• Sex: Male
• Age: 16 Years – 24 Years
• Healthy volunteers: Not accepted

Summary

In Vietnam, adolescent and young men who have sex with men (AYMSM) are among those most affected by HIV, and they also experience significant HIV-related mental health and stigma challenges. The study team proposes to adapt Project YES+ to address both mental health and internalized HIV stigma among AYMSM living with HIV in Vietnam. This research will build local capacity and develop networks for collaborative research on mental health and stigma in this population between Vietnam, Zambia and the United States.

Detailed description

The specific aims of this proposal are to (1) adapt Project YES+ to create To Hieu (I understand) to improve mental health and internalized HIV stigma for AYMSM living with HIV in Vietnam and (2) examine acceptability and feasibility of To Hieu among AYMSM living with HIV in Vietnam through a pilot randomized controlled trial.

Conditions

• Mental Disorder
• HIV Stigma

Interventions

Type	Name	Description
BEHAVIORAL	To Hieu (I understand)	Project YES+ was developed from two evidence-based interventions - Project Yes! and Self-Help Plus, based on Social Cognitive Theory (Project Yes!) and Acceptance and Commitment Therapy (Self-Help Plus). The youth-focused intervention component comprises 6 individual sessions with a youth peer mentor, 3 youth group sessions facilitated by a youth peer mentor and 5 group sessions to learn stress management skills. The original intervention was designed for 4 months and involves caregivers. The adaptation of Project YES+ for adolescents and young men who have sex with men living with HIV in Vietnam will make revisions on the content, frequency and delivery format of the intervention.

Timeline

• Start date: 2026-06-01
• Primary completion: 2027-11-30
• Completion: 2028-02-28
• First posted: 2026-04-07
• Last updated: 2026-04-07

Locations

1 site across 1 country: Vietnam