Trials / Completed
CompletedNCT07513103
Clinical Effectiveness of Tigecycline for Scrub Typhus.
Clinical Efficacy Analysis of Drug Use Tigecycline for Re-creation of Antimicrobial Agents for Treatment of Scrub Typhus.
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 31 (actual)
- Sponsor
- Jin Soo Lee · Academic / Other
- Sex
- All
- Age
- 19 Years – 100 Years
- Healthy volunteers
- Accepted
Summary
The goal of this randomized case-control study is to analysis of effectiveness of tigecycline in scrub typhus. The main question it aims to answer are: * \[question 1\]: Does tigecycline reduce fever faster than doxycycline in scrub typhus? * \[question 2\]: Is the use of tigecylcine tolerable in scrub typhus? Participants will assigned as doxycycline or tigecycline groups. Researchers will compare tigecycline group with doxycycline group, using defervescence time and adverse events.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | doxycycline | Doxycycline 100 mg orally every 12 hours for 7 days. |
| DRUG | Tigecycline (Tygacil) | Tigecycline 100 mg intravenously as a loading dose, followed by 50 mg intravenously every 12 hours for 5 days. |
Timeline
- Start date
- 2022-09-30
- Primary completion
- 2024-06-11
- Completion
- 2024-06-11
- First posted
- 2026-04-06
- Last updated
- 2026-04-06
Locations
3 sites across 1 country: South Korea
Source: ClinicalTrials.gov record NCT07513103. Inclusion in this directory is not an endorsement.