NCT07512219

Comparison Between Greater Occipital Nerve Block and Pulsed Radiofrequency in the Management of Chronic Migraine

Comparative Study of Greater Occipital Nerve Block and Pulsed Radiofrequency in the Management of Chronic Migraine : Clinical Outcomes and Neurophysiological Correlates A Prospective Randomized Study

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Comparative Study of Greater Occipital Nerve Block and Pulsed Radiofrequency in the Management of Chronic Migraine : Clinical Outcomes and Neurophysiological Correlates A Prospective Randomized Study

Conditions

• Chronic Migraine, Headache

Interventions

Type	Name	Description
DRUG	Greater occiptal nerve block	Injection Procedure: 1. Local skin infiltration with 1-2 mL of 1% lidocaine at puncture site. 2. GON block using 3-5 mL of local anesthetic, optionally combined with 20-40 mg triamcinolone ( Bilaterally ) 3. Needle placement confirmed by ultrasound visualization of the nerve and spread of injectate. 4. Observe patient for 15-20 minutes post-injection for immediate adverse events.
DEVICE	Pulsed radiofrequency	1. Introduce RF cannula adjacent to GON under ultrasound guidance. 2. Confirm sensory stimulation: paresthesia at occipital scalp at \<0.5 V. 3. PRF settings: * Temperature: ≤42°C * Pulse duration: 20 ms * Frequency: 2 Hz * Duration: 120 seconds per cycle, 2 cycles per side 4. Continuous monitoring of patient comfort and vital signs.

Timeline

• Start date: 2026-05-01
• Primary completion: 2026-11-01
• Completion: 2027-05-01
• First posted: 2026-04-06
• Last updated: 2026-04-06