NCT07510022

Hot Climate on Bleeding Tendency After Cardiac Surgery in Egyptian Patients

Effect of Hot Climate on Bleeding Tendency After Cardiac Surgery in Egyptian Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 400 (actual)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This work aimed to assess the effect of regional climatic differences on postoperative bleeding in Egyptian patients undergoing cardiac surgery with cardiopulmonary bypass, by comparing outcomes between patients from hot climate zones (Upper Egypt) and those from moderate climate zones (Lower Egypt).

Detailed description

Egypt experiences extremely high ambient temperatures, especially during the summer months, with daily highs frequently exceeding 40°C. Such climatic extremes can influence physiological homeostasis in surgical patients by altering fluid balance, cardiovascular strain, and hemostatic function. Seasonal and climatic variations have been linked to changes in cardiovascular surgical outcomes, including mortality, length of stay, and complication rates. Several large observational studies have noted increased bleeding or transfusion requirements in surgeries performed under certain environmental conditions, though findings remain inconsistent.

Conditions

• Hot Climate
• Bleeding Tendency
• Cardiac Surgery
• Egyptian Patients

Interventions

Type	Name	Description
PROCEDURE	Open heart surgery	Patients who underwent open heart surgery with cardiopulmonary bypass.

Timeline

• Start date: 2023-06-01
• Primary completion: 2025-06-01
• Completion: 2025-06-01
• First posted: 2026-04-03
• Last updated: 2026-04-03

Locations

1 site across 1 country: Egypt