NCT07509996

Risk Factors Affecting Growth in Thalassemic Children at AUCH

The Effect of Different Risk Factors on Growth Parameters of Thalassemic Patients in Assiut University Children Hospital

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 85 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 12 Months – 18 Years
• Healthy volunteers: —

Summary

Thalassemia major is a hereditary hemoglobinopathy characterized by ineffective erythropoiesis and severe anemia, necessitating lifelong blood transfusions(1,2). Regular transfusions lead to iron overload, a primary driver of growth retardation in affected children. Iron accumulation in tissues like the pituitary and liver disrupts growth hormone secretion and insulin-like growth factor-1 production.

Conditions

• Thalassemia Majors (Beta-Thalassemia Major)

Interventions

Type	Name	Description
OTHER	Non-interventional assessment of growth and risk factors in thalassemic children	No therapeutic intervention is applied. The study involves only observational assessment of clinical history, anthropometric measurements, laboratory investigations, and growth parameters in thalassemic children. This distinguishes it from interventional studies.

Timeline

• Start date: 2026-04-01
• Primary completion: 2027-04-01
• Completion: 2027-05-01
• First posted: 2026-04-03
• Last updated: 2026-04-03