NCT07509827

Evaluation of mHealth Intervention to Promote HIV Prevention and Overcome Stigma Among Transgender Women (EMPOW.HER)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 108 (estimated)
• Sponsor: Institute of HIV Research and Innovation Foundation, Thailand · Academic / Other
• Sex: Male
• Age: 18 Years – 29 Years
• Healthy volunteers: Not accepted

Summary

This study aims to develop and evaluate a multi-component mHealth intervention (mHC and FRESH) to reduce HIV-related and intersectional stigma and improve PrEP use among HIV-negative young transgender women (TGW) in Thailand.

Detailed description

This study uses a Multiphase Optimization Strategy (MOST) design to adapt, refine, and evaluate two mobile-based interventions: Mobile Healthy Choices (mHC) and Finding Respect and Ending Stigma around HIV (FRESH). The interventions are designed to address stigma, improve empowerment, and enhance uptake and adherence to HIV pre-exposure prophylaxis (PrEP). The study includes formative research, intervention adaptation, beta testing, and a pilot factorial randomized trial among TGW aged 18-29 in Bangkok, Thailand, with follow-up over 6 months

Conditions

• HIV Prevention
• HIV Related Stigma
• PrEP Adherence

Interventions

Type	Name	Description
BEHAVIORAL	Mobile Healthy Choices (mHC)+SPC	Intervention: * Behavioral: Mobile Healthy Choices (mHC) * Behavioral: Standard PrEP Counseling (SPC)
BEHAVIORAL	FRESH + SPC	Intervention: * Behavioral: FRESH (Finding Respect and Ending Stigma around HIV) * Behavioral: Standard PrEP Counseling (SPC)
BEHAVIORAL	mHC + FRESH + SPC	Intervention: * Behavioral: Mobile Healthy Choices (mHC) * Behavioral: FRESH * Behavioral: Standard PrEP Counseling (SPC)

Timeline

• Start date: 2024-08-01
• Primary completion: 2027-07-31
• Completion: 2028-07-31
• First posted: 2026-04-03
• Last updated: 2026-04-03

Locations

3 sites across 1 country: Thailand