NCT07508891

Characterisation of phenotYpes in aCute Heart faiLure patiEnts

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Universitätsklinikum Hamburg-Eppendorf · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

An observational cohort study to evaluate the benefit of functional parameters, radiomics and blood biomarkers to predict the outcome of patients with acute heart failure.

Detailed description

Heart failure is a condition with both a high burden of morbidity and mortality. Cases of acute heart failure are frequent in A\&E departments and a common reason for hospitalisation. The primary aim of this prospective, monocentric cohort study is to characterise distinct phenotypes of patients with acute heart failure (including all stages of cardiogenic shock) and to identify functional, radiological and circulating biomarkers to improve risk prediction for the individual patient. Hypotheses to inform future trial design will be generated. Biobanking is included to allow for future assessment of novel biomarkers.

Conditions

• Acute Heart Failure
• Decompensated Heart Failure
• Cardiogenic Shock

Timeline

• Start date: 2019-03-01
• Primary completion: 2030-12-31
• Completion: 2030-12-31
• First posted: 2026-04-02
• Last updated: 2026-04-02

Locations

1 site across 1 country: Germany