Clinical Trials Directory

Trials / Completed

CompletedNCT07508046

Clinical Study on the Expression of PHGDH and Its Prognostic Value in Colorectal Cancer Patients Receiving Immunotherapy

Status
Completed
Phase
Study type
Observational
Enrollment
100 (actual)
Sponsor
West China Hospital · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This study aims to evaluate the expression characteristics of PHGDH in tumor tissues based on the clinical data and pathological tissue samples of colorectal cancer patients who have previously received immunotherapy, and to analyze its correlation with patients' clinical features, immunotherapy efficacy, and survival prognosis, providing a basis for clarifying the clinical relevance of PHGDH.

Conditions

Interventions

TypeNameDescription
OTHERNo interventionNo therapeutic or experimental intervention was administered in this study. Participants were assigned to the PHGDH-high and PHGDH-low cohorts according to PHGDH expression in tumor tissues for observational analysis of clinical outcomes and treatment response.

Timeline

Start date
2025-11-01
Primary completion
2026-01-01
Completion
2026-01-01
First posted
2026-04-02
Last updated
2026-04-02

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT07508046. Inclusion in this directory is not an endorsement.

Clinical Study on the Expression of PHGDH and Its Prognostic Value in Colorectal Cancer Patients Receiving Immunotherapy (NCT07508046) · Clinical Trials Directory