NCT07507994

COM-B Model-based Behavioral Intervention on Safe Pesticide Use and Food Safety Practice Among Farmers

COM-B Model-based Behavioral Intervention on Safe Pesticide Use and Food Safety Practice Among Farmers in the North Mecha and Fogera Districts: a Randomized Controlled Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 572 (estimated)
• Sponsor: Bahir Dar University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study evaluates the effectiveness of a COM-B-based behavioral intervention to improve safe pesticide use and food safety practices among smallholder farmers in Ethiopia, using a cluster-randomized controlled trial design. A cluster-randomized controlled trial will be conducted in the North Mecha and Fogera districts. A total of 22 clusters (kebeles) will be randomly selected and allocated to intervention or control arms. Approximately 572 eligible farmers will be enrolled. The intervention will last 12 weeks, followed by a 4-week follow-up (total 16 weeks). Study Design: Interventional, Randomized, Parallel Assignment, Single-blind (assessor)

Detailed description

Pesticide use and food safety practices are critical public health concerns in Ethiopia, particularly among smallholder farmers who face frequent exposure to hazardous chemicals and unsafe food handling conditions. Improper pesticide use, including failure to follow label instructions, inadequate use of personal protective equipment (PPE), unsafe storage and disposal, and application under inappropriate environmental conditions, contributes to acute pesticide poisoning and long-term health effects. In addition, poor hygienic practices during the handling, storage, and transportation of agricultural produce increase the risk of food contamination and foodborne diseases. Despite growing evidence of these risks, most interventions have primarily focused on knowledge dissemination and regulatory enforcement, with limited success in achieving sustained behavioral change. Safe pesticide use and food safety practices are complex behaviors influenced by multiple interacting factors, including capability (knowledge and skills), opportunity (access to resources and supportive environments), and motivation (beliefs, intentions, and habits). This study applies the Capability, Opportunity, and Motivation-Behavior (COM-B) model as a theoretical framework to design and evaluate a comprehensive behavioral intervention targeting these determinants. The intervention aims to improve farmers' knowledge and practical skills, enhance access to enabling resources and social support, and strengthen motivation through risk communication, goal setting, and behavioral reinforcement strategies. A cluster randomized controlled trial will be conducted among smallholder farmers in the Fogera and North Mecha districts of the Amhara Region, Ethiopia. A total of 22 clusters (villages) will be randomly selected and allocated to intervention or control arms with proportional representation from each district. Eligible farmers within selected clusters will be enrolled, yielding a total sample size of approximately 572 participants. The intervention group will receive a structured COM-B-based behavioral intervention delivered over 12 weeks in three monthly cycles. Each cycle comprises four core sessions (approximately 4 hours each) delivered intensively within the first week of the month (Weeks 1, 5, and 9), resulting in 16 contact hours per cycle and a total of approximately 48 contact hours. The sessions target key behavioral domains: (1) enhancing capability through participatory education, demonstrations, and hands-on training; (2) creating supportive opportunities through community engagement, peer learning, and linkage with extension services; (3) strengthening motivation through goal setting, reflection, and behavioral reinforcement; and (4) promoting practice, integration, and feedback to facilitate real-life application. To reinforce behavior change, follow-up monitoring and supportive supervision will be conducted during the remaining weeks of each cycle through field visits, on-site coaching, group discussions, and behavioral review sessions. These activities aim to provide technical support, identify and address contextual barriers, and strengthen adherence to recommended practices. Following completion of the intervention, an additional 4-week follow-up period will be implemented to assess the translation of learned behaviors into routine practice, after which the endline assessment will be conducted. The control group will receive routine agricultural and health extension services without exposure to the structured intervention. Data will be collected at baseline and at 16 weeks post-enrollment (including the 12-week intervention and 4-week follow-up period). The primary outcomes are safe pesticide use practices and food safety practices, measured using structured composite indices. Secondary outcomes include self-reported acute pesticide poisoning symptoms and behavioral determinants aligned with the COM-B framework. The effectiveness of the intervention will be evaluated using a cluster-level analytical approach that accounts for intra-cluster correlation and repeated measurements. Analyses will follow the intention-to-treat principle, and intervention effects will be estimated using appropriate regression models, such as generalized estimating equations and difference-in-differences approaches, while controlling for potential confounders. This study is expected to generate robust evidence on the effectiveness of a theory-driven behavioral intervention in improving pesticide safety and food safety practices among smallholder farmers. The findings will contribute to the limited body of randomized controlled trial evidence in agricultural public health and provide practical guidance for designing scalable, behaviorally informed interventions to reduce pesticide-related health risks and improve food safety in low- and middle-income countries.

Conditions

• Pesticide Exposure
• Food Safety

Interventions

Type	Name	Description
BEHAVIORAL	COM-B-Based Behavioral Intervention	A structured COM-B-based behavioral intervention follows up to 16 weeks, including education, skills training, practical demonstrations, environmental support, and motivational strategies to improve safe pesticide use and food safety practices among farmers, including follow-up visits for reinforcement
OTHER	Active Comparator: Routine agricultural extension services	Participants will receive routine agricultural extension services and follow-up for 16 weeks

Timeline

• Start date: 2026-04-01
• Primary completion: 2026-10-30
• Completion: 2026-12-30
• First posted: 2026-04-02
• Last updated: 2026-04-02