NCT07506941

Study of Functional Decline and Care Pathways in Neurosurgical Patients Over 65 Years of Age

A Prospective, Multicenter, and Transnational Study of Functional Decline and Care Pathways in Neurosurgical Patients Over 65 Years of Age

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 209 (estimated)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

The GENEUS 1 study addresses this gap by characterizing the real-world profiles, outcomes, and care pathways of adults aged 65 years and older hospitalized in neurosurgery across France, Spain, and Portugal. This project represents the first multicentre, transnational initiative to integrate geriatric principles into neurosurgical practice and to evaluate both clinical and economic outcomes in this population.

Detailed description

This is a prospective, multicentre, multinational, observational study. Seven neurosurgical centres in France, Spain, and Portugal will participate. Each participant will be followed at three timepoints: V0 (Admission): baseline clinical and geriatric assessment. V1 (Discharge): length of stay, complications, and updated functional and cognitive status. V2 (3 months ±1 week): structured telephone follow-up or face-to-face visit to assess readmission, autonomy, and quality of life. A 12-month medico-economic component (only in France) will evaluate healthcare utilization and costs using clinical data, patient or caregiver questionnaires, and linkage with the Système National des Données de Santé (SNDS) in France.

Conditions

• Ageing and Geriatric Health

Timeline

• Start date: 2026-04-01
• Primary completion: 2026-12-01
• Completion: 2027-12-01
• First posted: 2026-04-02
• Last updated: 2026-04-02

Locations

6 sites across 3 countries: France, Portugal, Spain