NCT07505680

Time-restricted Feeding and Health

The Effect of Early Time-restricted Feeding in Metabolic Health - Differences Between Chronotypes.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Harokopio University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The purpose of this pilot, single-arm clinical trial is to assess the effects of time-restricted feeding on overall health, including body composition, glycemic and lipidemic profile, as well as appetite-regulating hormones, including glucagon-like peptides 1(GLP-1) oxyntomodulin, glucagon. Additionally, the study aims to evaluate the impact of this dietary pattern on circadian rhythm parameters, including acrophase, mesor, and amplitude.

Conditions

• Appetite
• Circadian Rhythm
• Metabolic Health
• Body Weight Control
• Glycemic and Insulinemic Response

Interventions

Type	Name	Description
OTHER	Time-Restricted Feeding	Ad libitum food intake from 08:00 to 18:00, followed by fasting from 18:00 to 08:00 for four weeks. Outside the eating window, water and limited amounts (1-2 servings) of very low-calorie items (e.g., tea, diet soft drinks, coffee, chewing gum \<4 kcal/serving) were permitted. The intervention focused exclusively on the timing of food intake and did not impose restrictions on the quantity or type of foods consumed.

Timeline

• Start date: 2025-06-04
• Primary completion: 2025-12-16
• Completion: 2025-12-16
• First posted: 2026-04-01
• Last updated: 2026-04-01

Locations

1 site across 1 country: Greece