NCT07505134

Exploring the Influence of Glucagon-like Peptide -1 (GLP-1) Medications on Food Cravings, Food Selection, and Food Intake Following Exposure to Food Advertisements

Exploring the Influence of GLP-1 Medications on External Food Cue Reactivity and Resultant Food Choice and Intake

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Penn State University · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this randomized control trial is to compare how food cravings, food selection, and food consumption change in response to frequent food advertisements compared to non-food advertisements in adults taking GLP-1 (weight loss) medications. The primary question we aim to answer is: do GLP-1 medications reduce an individual's vulnerability to external triggers that drive food cravings and consumption? Participants will: * report daily food consumption for a total of 10 days, * receive eight daily prompts to view food or non-food related advertisements, and respond to a short 9-question survey for 7 days, * answer several questionnaires, * and complete two in-person visits to complete a virtual reality food selection task.

Conditions

• GLP - 1

Interventions

Type	Name	Description
BEHAVIORAL	Food advertisements	Videos and images of food and beverage advertisements from popular brands and/or restaurants
BEHAVIORAL	Tech advertisements	Video and photo advertisements of popular tech tools

Timeline

• Start date: 2026-05-01
• Primary completion: 2026-08-01
• Completion: 2026-09-01
• First posted: 2026-04-01
• Last updated: 2026-04-01