NCT07504952

Investigating the Impact of Probiotics on Wellbeing in a Community

Effects of Probiotic Supplementation on Cognitive Lapses and Gastrointestinal Symptoms in a Non-Clinical Population: A Randomised, Placebo-Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 85 (actual)
• Sponsor: Loughborough University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to find out whether taking probiotics can improve thinking ability and gut (digestive) symptoms in healthy adults. The study will also explore whether probiotics affect mental health, alcohol cravings, and drinking and eating behaviours. The main questions it aims to answer are: * Do probiotics improve everyday thinking, attention, and memory? * Do probiotics reduce digestion issues or discomfort? * Do probiotics modulate alcohol cravings? * Do probiotics improve mood, stress, and anxiety levels? * Do probiotics influence drinking behaviour? * Do probiotics influence eating behaviour? Researchers will compare a probiotic supplement to a placebo (a look-alike product with no active ingredients) to see whether probiotics have real effects. Participants will be randomly assigned to one of these groups, and neither the participants nor the researchers will know who is receiving which treatment during the study. Participants will: * Take either a probiotic supplement or a placebo every day for 8 weeks * Complete online questionnaires about their mood, thinking, eating and drinking behaviours, and digestive health at the start and end of the study * Provide basic lifestyle and demographic information This study aims to better understand whether probiotics could be a simple and low-cost way to support cognitive function, digestive health and other wellbeing outcomes in generally healthy adults.

Conditions

• This Study Focus Focuses on a Non-clinical Sample of Generally Healthy Adults, and Whether Probiotics Offer Any Holistic Health Benefits

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic Arm	The participant will be randomly assigned to receive the probiotic, containing the active ingredient and live bacteria
DIETARY_SUPPLEMENT	Placebo Arm	The participant will be randomly assigned to receive the placebo, containing no active ingredient/live bacteria

Timeline

• Start date: 2025-09-28
• Primary completion: 2026-02-20
• Completion: 2026-03-01
• First posted: 2026-04-01
• Last updated: 2026-04-01

Locations

1 site across 1 country: United Kingdom