NCT07504887

Effects of Aerobic Exercise in Rheumatoid Arthritis

Evaluation of the Effects of Aerobic Exercise Therapy on Quality of Life, Functional Capacity, Mood, Fatigue, and Inflammatory Markers in Patients With Rheumatoid Arthritis

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 64 (estimated)
• Sponsor: Kutahya Health Sciences University · Academic / Other
• Sex: All
• Age: 30 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the effects of aerobic exercise therapy on quality of life, functional capacity, mood, and fatigue in patients with rheumatoid arthritis. Additionally, the study investigates the impact of aerobic exercise on inflammatory markers, pain, and disease activity.

Detailed description

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by joint inflammation, pain, and functional limitations. Exercise therapy is widely used in rehabilitation to improve functional capacity and quality of life in RA patients. In this study, patients with low disease activity RA will be divided into two groups: Standard medical treatment + education Standard medical treatment + education + aerobic exercise The aerobic exercise program will be conducted 5 days per week for 6 weeks. Outcomes including functional capacity (VO2 max), quality of life, fatigue, mood, and inflammatory markers will be assessed before and after the intervention.

Conditions

• Rheumatic Diseases
• Rheumatic Disorder

Interventions

Type	Name	Description
OTHER	Standard Medical Care (SMC)	Standard medical treatment
OTHER	Patient Education	Patient education
OTHER	Aerobic Exercise Group	Frequency: 5 days/week Duration: 6 weeks (30 sessions) Exercise intensity: 50-70% of Wmax Includes warm-up, aerobic phase, and cool-down

Timeline

• Start date: 2026-04-01
• Primary completion: 2026-12-31
• Completion: 2027-01-30
• First posted: 2026-04-01
• Last updated: 2026-04-01

Locations

1 site across 1 country: Turkey (Türkiye)