NCT07504718

The Effect of Cold Exposure on Physiological Markers

The Effect of Cold Water Immersion on Physiological Markers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Lithuanian Sports University · Academic / Other
• Sex: All
• Age: 18 Years – 36 Years
• Healthy volunteers: Accepted

Summary

The goal of this observational study is to examine how different physiological markers change over a two-day period after long-duration whole-body cold-water immersion in healthy young men and women. Specifically, the study aims to address the following questions: * How do kynurenine pathway metabolites change after cold exposure? * How do stress markers change after cold exposure? * How do cytokine levels change after cold exposure? * How do white blood cells count and distribution change after cold exposure?

Conditions

• Healthy Adult Participants

Interventions

Type	Name	Description
OTHER	Cold water immerssion	This intervention consisted of intermittent whole-body immersion in 14 °C water. After 20 min of immersion, the subject exited from the bath and rested for 10 min by sitting in the room environment, and then the same procedure was repeated. The cold stress continued until 170 min in total (120 min maximum total immersion time).

Timeline

• Start date: 2013-05-13
• Primary completion: 2018-05-06
• Completion: 2018-05-06
• First posted: 2026-04-01
• Last updated: 2026-04-07

Locations

1 site across 1 country: Lithuania