NCT07504172

Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity

Real-world Effectiveness and Dosing Patterns of Tirzepatide: A Multicentre Retrospective Observational Study in the Netherlands

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,700 (estimated)
• Sponsor: Radboud University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Tirzepatide is one of the new medications for the treatment of obesity. In clinical research people treated with Tirzepatide have weight loss up to 21%. But there is only a little bit of research showing the effect of Tirzepatide in clinical practice. In this retrospective observational study the investigators will evaluate the effectiveness of tirzepatide in routine clinical practice among adults with obesity in the Netherlands.The main questions it aims to answer are: * How much weight do patients lose after six months of treatment with tirzepatide combined with lifestyle coaching? * How is the medication dosed in daily practice? Researchers will use data from electronic health records of patients in multiple outpatient locations of the Dutch Obesity Clinic (NOK, Nederlandse Obesitas Kliniek).

Conditions

• Overweight , Obesity
• Obesity (Disorder)

Interventions

Type	Name	Description
DRUG	Tirzepatide	Initiating treatment with tirzepatide

Timeline

• Start date: 2026-04-01
• Primary completion: 2026-07-01
• Completion: 2026-08-01
• First posted: 2026-03-31
• Last updated: 2026-03-31

Locations

10 sites across 1 country: Netherlands

Regulatory

• FDA-regulated drug study