NCT07503847

Shared Decision-Making for Colorectal Cancer Screening in High-Risk First-Degree Relatives Aged 40-49

A Randomized Controlled Trial on Shared Decision-Making for Colorectal Cancer Screening Among High-Risk First-Degree Relatives Aged 40-49

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,286 (estimated)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 40 Years – 49 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of this study was to evaluate the impact of a constructed shared decision (SDM) intervention (offering an option between colonoscopy and immunochemical collapsible occult blood testing (fecal immunochemical test; FIT)) on improving the incidence of high colonoscopy stromal in patients aged 40-49 years with a close relative suffering from colorectal cancer, compared to standard care (direct referral for colonoscopy).

Conditions

• Colo-rectal Cancer
• Shared Decision Making
• Patient Decision Aid

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Colonoscopy	Participants underwent standard colonoscopy performed by experienced endoscopists following routine clinical procedures.
BEHAVIORAL	Shared Decision-Making	Participants received a shared decision-making intervention including educational materials and discussion with clinicians to choose between screening options.

Timeline

• Start date: 2025-09-01
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2026-03-31
• Last updated: 2026-03-31

Locations

1 site across 1 country: Taiwan