NCT07501442

Clinical Trial Evaluating the Efficacy and Safety of Uracil 0,5% Plasters in Oncology Patients Affected by Hand-foot Syndrome (HFS)

A Randomized, Single Blind, Parallel Groups, Clinical Trial Evaluating the Efficacy and Safety of Uracil 0,5%-Containing Plasters Versus "Lenitive Cream", in Oncology Patients Affected by Hand-foot Syndrome (HFS)

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Wooshin Labottach Co., Ltd. · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to learn if The Uracil plaster works to treat mild HFS in adults under chemiotherapy. It will also learn about the safety . The main questions it aims to answer are: Does Uracil Plaster lower the number of days participants need to reduce the HFS symptoms? What medical problems do participants have when using the Uracil plaster MD? Researchers will compare the Uracil plaster to a standard lenitive cream to see if Uracil Plaster works better to treat mild HFS. Participants will: Use the plaster or the cream 2/3 times day for 3 weeks Visit the hospital once every week for checkups and tests Keep a diary of their symptoms and the number of times they use the therapy

Conditions

• HFS

Interventions

Type	Name	Description
DEVICE	Uracil 0,5% plasters	Patients will applicate to hands and feet the plaster twice per day for 3 weeks to reduce the HFS grade.
DEVICE	lenitive cream	Patients will applicate the cream 3 times per day for 3 weeks to compare the change of HFS severity

Timeline

• Start date: 2026-07-01
• Primary completion: 2027-03-01
• Completion: 2027-04-01
• First posted: 2026-03-30
• Last updated: 2026-03-30

Locations

1 site across 1 country: Italy