NCT07500038

Evidence-Based Practice for the Management of Musculoskeletal Symptoms in Breast Cancer Patients Undergoing Endocrine Therapy: A Multicultural Perspective

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 289 (actual)
• Sponsor: Yuling CAO · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this implementation study is to evaluate the application of an evidence-based practice (EBP) program for managing musculoskeletal symptoms in breast cancer patients receiving endocrine therapy, from a multicultural perspective. The main questions it aims to answer are: Is the culturally adapted EBP program feasible and acceptable to implement in real-world clinical settings? Does the implementation of this program effectively reduce patients' musculoskeletal symptoms and improve their quality of life? Researchers will compare the group receiving the cross-culturally adapted evidence-based management with a group receiving standard routine care. During the study: Healthcare providers will implement the culturally tailored symptom management program. Participants will receive targeted health education and nursing guidance based on their cultural context. Researchers will collect data on how well the program is adopted (implementation outcomes), as well as evaluate changes in patients' joint symptoms and overall well-being at designated follow-up times (clinical outcomes).

Conditions

• Breast Neoplasms
• Aromatase Inhibitor-Associated Musculoskeletal Symptoms (AIMSS)

Interventions

Type	Name	Description
BEHAVIORAL	Culturally Adapted EBP Program	A comprehensive, culturally tailored symptom management program providing targeted health education, monitoring, and nursing guidance for musculoskeletal symptoms.
OTHER	Standard Routine Care	Standard clinical follow-up and general nursing care as routinely provided to patients receiving endocrine therapy.

Timeline

• Start date: 2024-12-01
• Primary completion: 2026-01-15
• Completion: 2026-03-10
• First posted: 2026-03-30
• Last updated: 2026-03-30

Locations

1 site across 1 country: China