NCT07496164

A Clinical Study to Assess the Effectiveness of Use of Three Experimental Denture Adhesives Compared to Using No-Adhesive

A Randomized, Controlled, Single-Blind, Cross Over Clinical Study Assessing the Maximum Maxillary Bite Force When Using Three Denture Adhesives Compared to Using No-Adhesive

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: HALEON · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of the proposed clinical study is to investigate the efficacy of three experimental denture adhesive creams to improve denture hold over a period of 13 hours.

Detailed description

This will be a single-center, controlled, randomized, single blind, 5 treatment-period, cross-over study to evaluate maximum maxillary bite force in a population of full maxillary denture wearers. A sufficient number of participants will be screened to randomize up to 60 participants to ensure at least 54 evaluable participants complete the entire study.

Conditions

• Denture Retention

Interventions

Type	Name	Description
DEVICE	Experimental Denture Adhesive 1	Denture adhesive cream
DEVICE	Experimental Denture Adhesive 2	Denture adhesive cream
DEVICE	Experimental Denture Adhesive 3	Denture adhesive cream
DEVICE	Poligrip Power Hold + Seal	Denture adhesive cream

Timeline

• Start date: 2026-03-30
• Primary completion: 2026-11-01
• Completion: 2026-11-01
• First posted: 2026-03-27
• Last updated: 2026-04-09

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study