Clinical Trials Directory

Trials / Completed

CompletedNCT07493343

EUSOL vs. PDGF Dressing for Diabetic Foot Ulcers

Comparison of EUSOL Dressing Versus Platelet Derived Growth Factor Dressing in Wound Contraction of Grade II Wagner Diabetic Foot Ulcers: A Randomized Controlled Trial

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
120 (actual)
Sponsor
Services Hospital, Lahore · Other Government
Sex
All
Age
30 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Diabetic foot ulcers are a major cause of morbidity and amputation. This randomized controlled trial will compare the efficacy of a traditional antiseptic dressing (EUSOL) with a modern biologic dressing containing Platelet-Derived Growth Factor (PDGF) in promoting wound contraction. The study aims to determine if PDGF dressing leads to better healing outcomes in patients with Grade II Wagner diabetic foot ulcers.

Conditions

Interventions

TypeNameDescription
PROCEDUREEUSOL DressingDaily dressing with freshly prepared Edinburgh University Solution of Lime (EUSOL) applied to the ulcer after standard debridement and cleansing.
PROCEDUREPlatelet-Derived Growth Factor (PDGF) DressingPDGF-based topical preparation applied to the ulcer surface every fourth day, covered by a secondary dressing. Interim dressing changes used normal saline only.

Timeline

Start date
2020-01-01
Primary completion
2025-12-31
Completion
2026-01-10
First posted
2026-03-25
Last updated
2026-03-25

Locations

1 site across 1 country: Pakistan

Source: ClinicalTrials.gov record NCT07493343. Inclusion in this directory is not an endorsement.