NCT07491393

Pharmacokinetic Study of the Use of Nefopam 30 mg Tablets in Patients Suffering From Acute Pain in Rheumatology

• Status: Not Yet Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: University Hospital, Rouen · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Nefopam is a non-opioid analgesic approved for the symptomatic treatment of acute pain, particularly postoperative pain. The HAS has authorized nefopam tablet, while emphasizing the lack of bibliographic data on both the pharmacokinetic and clinical aspects. The aim of this study is to evaluate the pharmacokinetics of nefopam tablets.

Conditions

• Acute Rheumatic Pain

Interventions

Type	Name	Description
DRUG	Nefopam administration and prelevment	Catheter placement, blood samples taken from H0 to H12 after each dose of nefopam in 4mL lithium heparin tubes without separating gel (9 samples per dose of nefopam)

Timeline

• Start date: 2026-04-01
• Primary completion: 2027-04-07
• Completion: 2027-04-07
• First posted: 2026-03-24
• Last updated: 2026-03-24

Locations

1 site across 1 country: France