NCT07490106

Benefits of Early Collaboration Between Oncologists and Palliative Care Physicians in Cases of Unplanned Hospitalization for Patients With Metastatic Cancer

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 493 (estimated)
• Sponsor: Centre Oscar Lambret · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a multicenter, national, interventional, cluster-randomized study, "stepped wedge" design. This study includes patients with metastatic or locally advanced digestive, gynecological, ENT, or sarcoma cancer, currently undergoing systemic palliative treatment and hospitalized on an unscheduled basis. The study will aim to evaluate the impact of early palliative care implementation for patients with metastatic or advanced cancer identified during an unplanned hospitalization.

Detailed description

This study will aim to evaluate the effectiveness of early palliative care for patients with metastatic or advanced cancer identified through unscheduled hospitalization in terms of reducing "aggressive" treatment. Other objectives of the study include : Compare approaches in terms of overall survival, treatment toxicities, advance directives, quality of life, anxiety, and depression. * Describing care according to the organization at the time of inclusion. * Evaluating the economic impact of early palliative care in patients with metastatic or advanced cancer through a medico-economic analysis combining cost-effectiveness and cost-utility analysis. * Evaluating interactions between the various stakeholders (palliative care physicians, supportive care physicians, oncologists).

Conditions

• Cancer
• Sarcoma Metastatic
• Gynaecologic Cancer
• Digestive Cancers
• ENT Cancer
• Metastatic Cancer or Locally Advanced

Interventions

Type	Name	Description
OTHER	Early integrated palliative care	Patients receive early integrated palliative care at the time of unplanned hospitalization for metastatic or advanced cancer. The intervention includes: * A palliative care consultation * A consultation with the treating oncologist * A multidisciplinary onco-palliative meeting to define a coordinated care plan
OTHER	Usual oncological care	Patients receive standard oncological care according to institutional practices. Palliative care is provided only when clinically indicated, without systematic early consultation at the time of unplanned hospitalization.

Timeline

• Start date: 2026-04-01
• Primary completion: 2031-04-01
• Completion: 2031-04-01
• First posted: 2026-03-24
• Last updated: 2026-03-24

Locations

1 site across 1 country: France