NCT07486284

Ultrasound Elastography of Carpal Tunnel Syndrome

Study on the Characteristics of Ultrasound Elastography in the Evaluation of Carpal Tunnel Syndrome

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 80 (estimated)
• Sponsor: Da Nang Family General Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Carpal Tunnel Syndrome (CTS) is the most common peripheral nerve compression disorder in adults. Although electromyography (EMG) is the current gold standard for diagnosis, it is invasive, time-consuming, and may yield false-negative results. Ultrasound elastography, including shear wave elastography and strain elastography, enables non-invasive assessment of median nerve stiffness, reflecting fibrosis and edema. However, data on the combined use of elastography and microvascular imaging in CTS are still limited in Vietnam. This study aims to evaluate the value of advanced ultrasound techniques in diagnosing CTS and grading disease severity, as well as their correlation with clinical symptoms and EMG findings

Conditions

• Carpal Tunnel Syndrome (CTS)

Interventions

Type	Name	Description
PROCEDURE	Ultrasound Elastography	* Shear Wave Elastography (SWE): * Performed in the longitudinal plane at the carpal tunnel inlet. * A Region of Interest (ROI) of 1mm will be placed on the median nerve (excluding epineurium). * Stiffness will be measured in kilopascals (kPa). * Three measurements will be taken and averaged. * Strain Elastography (SE): * Assessed using a color map overlay (Blue/Green/Red). * Grading scale (1-4): Grade 1 (Soft/Red) to Grade 4 (Hardest/Blue).

Timeline

• Start date: 2025-04-15
• Primary completion: 2026-03-20
• Completion: 2026-04-15
• First posted: 2026-03-20
• Last updated: 2026-03-20

Locations

1 site across 1 country: Vietnam