NCT07485153

A Study to Compare Two Different Sleep Tests in Participants With No Symptoms or Early Symptoms of Alzheimer's Disease

A Study to Assess the Use of the Somfit, an Ambulatory Electroencephalogram-Based Digital Health Technology, Compared With Polysomnography to Evaluate Sleep Architecture in Individuals With Asymptomatic or Early Alzheimer's Disease

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 35 (estimated)
• Sponsor: Eli Lilly and Company · Industry
• Sex: All
• Age: 55 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the results of two different sleep tests in Alzheimer's patients with no symptoms or early symptoms. Participants will undergo two simultaneous sleep tests (polysomnography) in a sleep laboratory for two nights and one sleep test at home for three nights. For each participant, the study will last at least a week and will last up to three months.

Conditions

• Alzheimer's Disease
• Early Alzheimer's Disease
• Memory Problems

Interventions

Type	Name	Description
DEVICE	Mobile EEG	Device measures electrical activity in the brain, pulse rate, blood oxygen saturation levels, changes in blood flow and volume, motion and snoring.
DEVICE	Activity Monitor	Device monitors physical movement.
DEVICE	Sleep Study	In-Laboratory overnight assessment using EEG, electromyography to measure muscle movement, eye movement, electrical activity in the heart, blood oxygen saturation levels and breathing levels.

Timeline

• Start date: 2026-03-01
• Primary completion: 2026-09-01
• Completion: 2026-09-01
• First posted: 2026-03-20
• Last updated: 2026-03-20

Locations

1 site across 1 country: Singapore