NCT07485127

Comparison Between Dexamethasone and Dexmedetomidine in Spinal Anesthesia for Cases With Fracture Pelvis Fixation

Comparison Between Dexamethasone and Dexmedetomidine as Adjuvant to Bupivacaine in Spinal Anesthesia for Cases With Fracture Pelvis Fixation Comparative Randomized Study

• Status: Active Not Recruiting
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to compare dexamethasone and dexmedetomidine as adjuvant to bupivacaine in fracture pelvis fixation as regard duration of sensory block and postoperative pain management.

Detailed description

Place of the study: Sohag University Hospitals after approval from the institutional ethical committee. Study Design: This prospective comparative study will be conducted on patients with fracture pelvis at the Department of Anesthesia, Intensive Care, and Pain Management,in Sohag University Hospitals after approval of the Research Ethical Committee. Study period: From February 2026 to August 2026.

Conditions

• Fracture Pelvis

Interventions

Type	Name	Description
DRUG	60 patients will be involved, half patients will receive 13mg bupivacaine + 4 mg dexamethasone. The other half will receive 13mg bupivacaine + 4 mg dexmedetomidine. All will be monitored closely.	Intraoperative and postoperative pain management

Timeline

• Start date: 2026-02-08
• Primary completion: 2026-08-31
• Completion: 2026-08-31
• First posted: 2026-03-20
• Last updated: 2026-03-20

Locations

1 site across 1 country: Egypt