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Not Yet RecruitingNCT07484893

A Study to Evaluate the Safety, PK, and Immunogenicity of Recombinant Human Hyaluronidase in Healthy Subjects

A Phase I Clinical Study to Evaluate the Safety, Pharmacokinetics, and Immunogenicity of Recombinant Human Hyaluronidase in Healthy Chinese Adult Male Subjects

Status
Not Yet Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
24 (estimated)
Sponsor
Shanghai Henlius Biotech · Industry
Sex
Male
Age
18 Years – 45 Years
Healthy volunteers
Accepted

Summary

The study is being conducted to evaluate the safety, pharmacokinetics, and immunogenicity of recombinant human hyaluronidase in healthy Chinese adult male subjects.

Conditions

Interventions

TypeNameDescription
DRUGrecombinant human hyaluronidaseHLXTE-HAase02 is a proprietary recombinant human hyaluronidase, with a molecular weight of approximately 49 kDa, is expressed in Chinese Hamster Ovary (CHO) cells and is intended for formulation development.

Timeline

Start date
2026-05-14
Primary completion
2026-08-25
Completion
2026-10-24
First posted
2026-03-20
Last updated
2026-03-20

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT07484893. Inclusion in this directory is not an endorsement.

A Study to Evaluate the Safety, PK, and Immunogenicity of Recombinant Human Hyaluronidase in Healthy Subjects (NCT07484893) · Clinical Trials Directory