Clinical Trials Directory

Trials / Completed

CompletedNCT07484074

A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Intravitreal OLN324

A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Two Different Formulations of Intravitreal OLN324 in Adult Participants With Either Neovascular (Wet) Age-related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME)

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
164 (actual)
Sponsor
Ollin Biosciences, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Intravitreal OLN324

Detailed description

A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Two Different Formulations of Intravitreal OLN324 in Adult Participants With Either Neovascular (Wet) Age-related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME)

Conditions

Interventions

TypeNameDescription
DRUGFaricimabIntravitreal Injection
DRUGOLN324Intravitreal Injection

Timeline

Start date
2025-02-12
Primary completion
2025-10-10
Completion
2025-12-09
First posted
2026-03-19
Last updated
2026-03-19

Locations

30 sites across 2 countries: United States, Puerto Rico

Regulatory

Source: ClinicalTrials.gov record NCT07484074. Inclusion in this directory is not an endorsement.