Trials / Not Yet Recruiting
Not Yet RecruitingNCT07478848
Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas
A Pilot Trial of Bridging Radiation Therapy With Oral Vancomycin for Patients With B-cell Lymphomas Undergoing CAR-T Therapy
- Status
- Not Yet Recruiting
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 14 (estimated)
- Sponsor
- Abramson Cancer Center at Penn Medicine · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This clinical trial assesses whether it is feasible to use radiation therapy with vancomycin prior to CAR T-cell therapy for patients with large B-cell lymphomas
Conditions
- Large B Cell Lymphoma
- Non Hodgkin Lymphoma (NHL)
- Diffuse Large B Cell Lymphoma (DLBCL)
- Diffuse Large B Cell Lymphoma Refractory
- Diffuse Large B Cell Lymphoma Relapsed
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Vancomycin 125mg | oral |
Timeline
- Start date
- 2026-04-07
- Primary completion
- 2029-01-01
- Completion
- 2029-01-01
- First posted
- 2026-03-18
- Last updated
- 2026-03-18
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT07478848. Inclusion in this directory is not an endorsement.