NCT07474935

Targeting Real World Usage In Stroke Treatment

TRUST Registry - Targeting Real World Usage In Stroke Treatment A WallabyPhenox Hemorrhagic Stroke Registry

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 5,000 (estimated)
• Sponsor: Phenox GmbH · Industry
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

TRUST Registry is an observational, prospective, long-term, post-market surveillance registry of subjects treated with WallabyPhenox flow modulation devices, stent systems, bifurcation aneurysm implants including their HPC variants (Hydrophilic Polymer Coating) where applicable as well as coil systems, and other adjunctive medical devices. The overarching purpose of this registry is to carry out a proactive gathering, recording, and analysis of data on the safety, performance and usability of the devices as applied within the routine practice of the participating registry sites.

Conditions

• Saccular and Fusiform Aneurysms
• Pseudoaneurysm
• Vascular Dissection
• Perforation
• Bifurcation Aneurysms
• Stenosis
• Neurovascular Abnormalties
• Wide-neck Aneurysm
• Intracranial Aneurysms

Interventions

Type	Name	Description
DEVICE	Aneurysm Treatment with a Neurovascular Flow Diverter	Treatment of aneurysms (saccular or fusiform) and pseudoaneurysms with a Neurovascular Flow Diverter. This includes p64, p64 MW, p64 MW HPC, p48 MW and p48 MW HPC.
DEVICE	Dissection Treatment with a Neurovascular Flow Diverter	Treatment of vascular dissections in the acute and chronic phases with a Neurovascular Flow Diverter. This includes p64, p64 MW, p64 MW HPC, p48 MW and p48 MW HPC.
DEVICE	Perforation Treatment with a Neurovascular Flow Diverter	Treatment of vascular perforations with a Neurovascular Flow Diverter. This includes p64, p64 MW, p64 MW HPC, p48 MW and p48 MW HPC.
DEVICE	Arteriovenous Fistula treatment with a Neurovascular Flow Diverter	Treatment of Arteriovenous fistula with a Neurovascular Flow Diverter. This includes p64, p64 MW, p64 MW HPC, p48 MW and p48 MW HPC.
DEVICE	Aneurysm Treatment with Neurovascular Stent System	Treatment of saccular and fusiform aneurysms as well as pseudoaneurysms with pEGASUS HPC. pEGASUS HPC is to be used in combination with coils.
DEVICE	Atherosclerotic vascular stenosis Treatment with Neurovascular Stent System	Atherosclerotic vascular stenosis of intracranial arteries treated with pEGASUS HPC.
DEVICE	Dissection Treatment with Neurovascular Stent System	Treatment of vascular dissections in the acute and chronic phases with pEGASUS HPC.
DEVICE	Aneurysm treatment with Bifurcation Aneurysm Implant	Treatment of intracranial bifurcation aneurysms with pCONUS 2 or pCONUS 2 HPC.
DEVICE	Aneurysm treatment with Avenir Coil System	Treatment of intracranial aneurysms with the available variants of the Avenir Coil System.
DEVICE	Arteriovenous fistula treatment with Avenir Coil System	Treatment of arteriovenous fistula with the available variants of the Avenir Coil System.

Timeline

• Start date: 2026-01-29
• Primary completion: 2036-01-01
• Completion: 2041-01-01
• First posted: 2026-03-16
• Last updated: 2026-03-16

Locations

13 sites across 5 countries: France, Germany, Italy, Slovakia, Switzerland