NCT07472062

Development of a Non-Invasive Prognostic Test for Graves Orbitopathy

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: University Hospital, Ghent · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this research project is to develop a non-invasive, simple, robust, and sensitive prognostic test that can identify hyperthyroidism patients who are at risk of developing Graves' Orbitopathy. This phase of the study is a research phase in which we analyze blood samples and tear fluid using standard laboratory equipment and software. The aim is to identify biomarkers that can detect patients at risk of developing Graves' Orbitopathy. Offering more personalized advice, treatment, and follow-up could potentially prevent the clinical consequences or limit their severity.

Conditions

• Graves Orbitopathy
• Hyperthyroidism

Interventions

Type	Name	Description
OTHER	Schirmer's test	Collection of tears with Schirmer's test

Timeline

• Start date: 2023-05-13
• Primary completion: 2024-06-25
• Completion: 2026-12-31
• First posted: 2026-03-16
• Last updated: 2026-03-16

Locations

1 site across 1 country: Belgium