NCT07469826

Bupivacaine Alone vs Bupivacaine With Tramadol in Local Anesthesia Procedures

Efficacy of Bupivacaine Alone and Bupivacaine With Tramadol in Local Anesthesia Procedures

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Jinnah Postgraduate Medical Centre · Other Government
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study looked at two different medicines used during local anesthesia to control pain after surgery. Investigators compared bupivacaine alone with bupivacaine mixed with tramadol. Both medicines are commonly used to numb the surgical area and reduce pain. The investigators included 100 adult patients who had minor surgeries under local anesthesia. Half received only bupivacaine, and the other half received bupivacaine combined with tramadol. After surgery, patients were asked to rate their pain at 4, 8, and 24 hours. The results showed that patients who received bupivacaine with tramadol felt less pain, especially at 24 hours after surgery, compared to those who received bupivacaine alone. In simple words: Adding tramadol to bupivacaine helps reduce pain better than bupivacaine alone. This method may help patients recover faster, feel more comfortable, and need fewer pain medicines after surgery.

Conditions

• Post Operative Pain, Acute

Interventions

Type	Name	Description
DRUG	Tramadol	A single dose of 1 mg/kg tramadol at the surgical site
DRUG	Bupivacaine	Single dose 0.5 ml/kg of 0.25% Bupivacaine at surgical site

Timeline

• Start date: 2022-10-10
• Primary completion: 2023-04-10
• Completion: 2023-05-10
• First posted: 2026-03-13
• Last updated: 2026-03-13

Locations

1 site across 1 country: Pakistan