NCT07469527

Effects of Feel Free® Classic Tonic on Stress and Pharmacokinetics in Healthy Adults

A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Effects of Feel Free® Classic Tonic on Self-Perceived Stress and Pharmacokinetic Profile in Healthy Adults

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 165 (estimated)
• Sponsor: Botanic Tonics, LLC · Industry
• Sex: All
• Age: 21 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This study is being conducted to assess the effects of the Feel Free® Classic Tonic on stress in healthy adults. The goal is to see whether the tonic can help reduce self-perceived and physiological stress and provide information on how its ingredients are processed in the body.

Detailed description

This is a randomized, double-blind, parallel, 3-arm, placebo-controlled study to assess the effects of two dose levels of the Feel Free® Classic Tonic on stress in healthy adults. The primary goal is to evaluate how the tonic affects self-reported and physiological measures of stress and anxiety. A pharmacokinetic sub-study will assess how the tonic's components are absorbed and processed. The tonic contains kava and kratom, botanicals traditionally used for relaxation and mood support, and early data suggest it is generally well tolerated.

Conditions

• Anxiety
• Physiological Stress
• Stress

Interventions

Type	Name	Description
OTHER	Placebo	Placebo
OTHER	Kava and Kratom Herbal Supplement	Feel Free Classic Tonic Dose 1 (TP1)
OTHER	Kava and Kratom Herbal Supplement	Feel Free Classic Tonic Dose 2 (TP2 - Half Strength)

Timeline

• Start date: 2026-03-07
• Primary completion: 2026-09-30
• Completion: 2026-10-14
• First posted: 2026-03-13
• Last updated: 2026-04-02

Locations

1 site across 1 country: Canada