Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07468838

Feasibility Study of Urinary cfDNA Analysis as a Non-invasive Monitoring Tool in Patients With Prostate or Bladder Cancer

Feasibility Study of Circulating Tumour DNA Analysis in Urine (Urinary cfDNA) as a Non-invasive Monitoring Tool in Patients With Prostate or Bladder Cancer

Status
Not Yet Recruiting
Phase
Study type
Observational
Enrollment
25 (estimated)
Sponsor
Institut Cancerologie de l'Ouest · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The UroDNA study is a feasibility study (RIPH category 3) aimed at evaluating the analysis of circulating tumour DNA in urine (urinary cfDNA) as a non-invasive monitoring tool in patients with prostate or bladder cancer. Urine samples will be collected at different times during the course of treatment to define the optimal conditions for cfDNA collection, extraction and analysis, and to explore the detection of tumour mutation profiles. This study does not involve any experimental treatment. Its objective is to validate the technical and clinical feasibility of a molecular monitoring urine test, which could offer a simple and non-invasive alternative to improve the management of urological cancers.

Detailed description

Patients will be included as they are admitted to the facility. If they agree to participate, two urine samples will be collected at the start of treatment and at the end of the treatment sequence.

Conditions

Timeline

Start date
2026-05-01
Primary completion
2027-12-01
Completion
2027-12-01
First posted
2026-03-13
Last updated
2026-03-16

Source: ClinicalTrials.gov record NCT07468838. Inclusion in this directory is not an endorsement.